David A Keays Selected Research

Lissencephaly

1/2017	Brain-specific knockin of the pathogenic Tubb5 E401K allele causes defects in motor coordination and prepulse inhibition.
10/2015	The Expression of Tubb2b Undergoes a Developmental Transition in Murine Cortical Neurons.
11/2007	Large spectrum of lissencephaly and pachygyria phenotypes resulting from de novo missense mutations in tubulin alpha 1A (TUBA1A).
1/2007	Mutations in alpha-tubulin cause abnormal neuronal migration in mice and lissencephaly in humans.

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David A Keays Research Topics

Disease

4	Lissencephaly 01/2017 - 01/2007
2	Polymicrogyria 01/2017 - 10/2015
2	Microcephaly 10/2016 - 10/2015
2	Nervous System Diseases (Neurological Disorders) 10/2015 - 01/2014
1	Motor Disorders 01/2017
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2017
1	Neurodevelopmental Disorders 01/2017
1	Intellectual Disability (Idiocy) 02/2014
1	Periventricular Nodular Heterotopia 11/2013
1	Diamond-Blackfan Anemia (Anemia, Diamond Blackfan) 01/2013
1	Classical Lissencephalies and Subcortical Band Heterotopias 01/2012
1	Pain (Aches) 05/2004
1	Mental Disorders (Mental Disorder) 11/2003

Drug/Important Bio-Agent (IBA)

5	TubulinIBA 01/2017 - 01/2007
2	Proteins (Proteins, Gene)FDA Link 02/2014 - 11/2013
1	RNA Splice SitesIBA 10/2016
1	GPI-Linked ProteinsIBA 02/2014
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2014
1	Guanine Nucleotide Exchange Factors (Guanine Nucleotide Exchange Factor)IBA 11/2013
1	ADP-Ribosylation Factors (ADP-Ribosylation Factor)IBA 11/2013
1	FilaminsIBA 11/2013
1	ribosomal protein S7IBA 01/2013
1	DNA (Deoxyribonucleic Acid)IBA 01/2012
1	alpha-conotoxin Vc1.1IBA 05/2004
1	Hydroxyproline (4 Hydroxyproline)IBA 05/2004
1	1-Carboxyglutamic Acid (1 Carboxyglutamic Acid)IBA 05/2004
1	Amino Acids FDA Link 05/2004
1	Peptides (Polypeptides)IBA 05/2004
1	Ethylnitrosourea (N-Ethyl-N-nitrosourea)IBA 11/2003